کاهش میزان پراکسیداسیون لیپید ها (مالون دی آلدئید) در بیماران دیابتی نوع II با مصرف پودر گیاه کندل کوهی

Introduction: Increased blood glucose is One of the main causes oxidative stress production in diabetes patients and ultimately creating complications cardiovascular- vascular. The aim of our study was to investigate the effecting of Dorema aucheri plant powder on amount the per oxidation lipid in diabetic patients. Methods: This study Was performed as double-blind randomized controlled clinical trial, between 150 patients with type 2 diabetes at diabetes research Center in Yazd . By dividing the patients into three groups,respectively, daily 100 and 500 mg plant capsules and placebo was administered. Blood samples were taken before and after taking the plant powder. After the measurement, the data with software SPSS software (version 16), and with a confidence level of 95% and P <0.05, were analyzed. Results: The mean malondialdehyde, before and after taking ,respectively, in the placebo group: 0 /59 &plusmn;0/03&nbsp; and 0/58&plusmn;0/03, in 100 mg dose groups 0/44&plusmn;0/07 and 0/41&plusmn;0/09(P =0/051) and for the 500 mg dose, respectively, 0/45&plusmn;0/07and 0/26&plusmn;0/04 mM. In the 500 mg dose groups, blood lipid index and blood glucose after consuming of plant powder had a significant reduction. Conclusion: This study showed that consumption of plant powder bilhar proportional decrease in plasma parameters (blood glucose, triglycerides, cholesterol), and lipid peroxidation (MDA) in patients diabetes.